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 C17 Skin and Connective Tissue Diseases D017437 +
  C17.800 Skin Diseases D012871 +
   C17.800.621 Pigmentation Disorders D010859 +
    C17.800.621.250 Cafe-au-Lait Spots D019080 
 C23 Pathological Conditions, Signs and Symptoms D013568 +
  C23.888 Signs and Symptoms D012816 +
   C23.888.885 Skin Manifestations D012877 +
    C23.888.885.250 Cafe-au-Lait Spots D019080